I'm having trouble backing up all of my devices to itunes. When I right click on my device, there is not an option to create a backup listed anymore. It also makes no attempt to automatically backup when I sync. I have tried uninstalling itunes,but it did not make any difference. When I reinstalled it, all my apps and music was already there. All of my old backups were there too. Any ideas on this?
Any help would be greatly appreciated!

On open a terminal window (mac) or command prompt (windows) and run

Mac:
defaults write com.apple.iTunes DeviceBackupsDisabled -bool false

Windows 32bit:
"%ProgramFiles%\iTunes\iTunes.exe" /setPrefInt DeviceBackupsDisabled 0

Windows 64bit:
"%ProgramFiles(x86)%\iTunes\iTunes.exe" /setPrefInt DeviceBackupsDisabled 0

No need to download an unknown/untrusted app that runs the equivalent of a one line command

I think there is something that has disabled your back up feature and it has nothing to do with itunes, anyway. there is something called "itunes backup disabler" once you download it you'll have two options
1. enable backup
2. disable backup
Once you get it, click on enable and hope this will help you.
More reviews: How to transfer iPod/iPhone/iPad to computer or iTunes
It includes the transferring of music, photos, videos, SMS, Contact ect. between iPod/iPhone/iPad and computer(PC or Mac).

Originally Posted by markhoward

I think there is something that has disabled your back up feature and it has nothing to do with itunes, anyway. there is something called "itunes backup disabler" once you download it you'll have two options
1. enable backup
2. disable backup
Once you get it, click on enable and hope this will help you.

You may have neglected to note the footnote in Olethros's post -- he referenced this (and other software of this type specifically). The 'iPhone Backup Disabler' does exactly what Olethros recommended the OP do. There's no reason to download the software, the change is a single command, and Olethros posted it. That is all the software does.

Again, there's no reason to download software to do something that is just a single command.

Have you checked to see if "Back up to this computer" is checked under the Summary tab in Devices?

Here is a list of some popular 3rd party apps which would allow you to create a backup of your iphone to your computer:

Comparison of iPod, iPhone & iPad backup software

Originally Posted by Howtolifemore

anyway, you can ask 3rd pary app for help such as iphone to computer transfer, on windows or mac, can backup any data on iphone freely. I got one.

iTunes can sometimes refuse to backup jailbroken iPhones. Numerous errors on the desktop can case this as well.
The simple thing to try, of course, is reboot the phone. If that doesn't work, more significant troubleshooting is needed. If you don't want to bother and the sync PC is a laptop, you can actually bring it and your iPhone to an Apple genius bar and they'll figure it out (not suggested for jailbroken devices, of course.)